Cough Science News
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
This month’s roundup explores placebo effects in RCC trials, the role of interoception in chronic cough, and the cost burden of persistent symptoms, plus insights from Dr. Nadia Giannetti.
New key cough science publications, Actigraph x Hyfe partnership and more
This year marked significant progress in cough monitoring, solidifying cough as a valuable biomarker in diverse therapeutic areas
New findings on refractory chronic cough (RCC), pulmonary tuberculosis, and pulmonary fibrosis. Plus latest white papers by Hyfe.
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News, August 2024 - Explore studies on cough variability, acute cough duration, and the cost burden of chronic cough. Plus, discover the world’s most comprehensive collection of cinematic coughs and upcoming events in cough science
CougH Science News July 2024 - latest in cough science. Insights on cough detection algorithms, pulmonary fibrosis, asthma diagnosis from cough sounds, and more. Plus, watch expert discussions and stay updated on upcoming events
Hyfe Cough Science News, June 2024. Latest research on cough in fibrotic ILD, high-dose inhaled corticosteroids for chronic cough, and family physicians’ approaches to managing chronic cough. Plus, insights from leading researchers and upcoming events
Cough Science News May 2024 - studies on cough monitoring for COVID-19 surveillance, the effectiveness of codeine for chronic cough, factors in refractory cough in IPF, and more. Plus, insights from researchers and upcoming events
Hyfe Cough Science News, March 2024 - insights on chronic cough management in the UK, common triggers in cough hypersensitivity, and a review of treatments for refractory cough. Plus, expert Q&A and upcoming cough science events.
Key Takeaway: The study found a significant correlation between aggregated cough count collected by a sensor in an emergency room and positive Covid-19 cases in the hospital (Pearson correlation of 0.40). Predictions of Covid-19 based on cough count outperformed predictions based on the number of patients presenting with fever.
Why It Matters: Fever monitoring is a widely used but somewhat intrusive method of syndromic surveillance. Cough monitoring may provide a more passive, but still real-time, alternative, or it could be combined with fever to generate more accurate predictive models. Integrating cough monitoring into syndromic surveillance might improve our ability to manage the next pandemic.
Key Takeaway: In a multicenter prospective study of 305 patients with RCC/UCC, just 16.7% responded clearly to codeine with rapid improvement in objective cough frequency and severity scores over the course of the first week following treatment. A further 18.7% were partial codeine responders and 20.3% were non-responders.
Why It Matters: This study is the first to characterize patients with RCC/UCC responding to codeine in a real-world patient registry - and the first to include continuous monitoring of objective cough frequency for one week following treatment (for a subset of patients). The high rate of poor response to codeine underscores the big unmet medical need in RCC/UCC.
Key Takeaway: The study reviewed IPF patients and found several clinical features of those with refractory chronic cough that differed from those without chronic cough: lower BMI, lower FVC, traction bronchiectasis and distorted airway architecture vs almost normal airway architecture on HRCT scans.
Why It Matters: Despite the small cohort size, the findings point to a potential mechanism for refractory chronic cough in IPF. This finding could form the basis for improved treatments for cough in IPF patients.
Exploring t Possibilities of Longitudinal Cough Data
Dr Zimmer spoke with us about her research into the value of cough as a biomarker for improving respiratory outcomes, particularly in tuberculosis (TB). Through multiple studies, she is examining the potential of cough for screening for TB, as well as for monitoring treatment.
“In my second study, which examines cough frequency over time, I hypothesize that cough frequency generally decreases during the initial weeks of TB treatment, and thus may help inform treatment monitoring.”
Dr Alex Zimmer
PhD student in Epidemiology at McGill University
