28.9B
Datapoints Processed61.8M
Coughs Detected161
Countries53
Clinical TrialsMaking Cough Count
Establishing cough as a routinely measured biomarker and endpoint to advance clinical research and transform respiratory care.
Establishing cough as a routinely measured biomarker and endpoint to advance clinical research and transform respiratory care.
Hyfe's technology powers clinical trial endpoints at pharmaceutical companies and medical device manufacturers, innovative research at academic institutions, and cough insights for healthcare organizations worldwide.
Cough is one of the most common symptoms in medicine, yet it remains unmeasured. Hyfe has built the world’s most advanced acoustic AI system for detecting and monitoring cough, enabling a new era of respiratory health.
Demonstrated through peer-reviewed studies and clinical trials across the world.
All detection happens on-device. No conversations are listened to or recorded, and no audio ever leaves the user’s device.
Built for advancing science, clinical research, and precision healthcare.
From clinical trials to wellness, Hyfe’s category-defining technology powers a growing suite of applications, each tailored to a different stage of the cough science journey.
Continuous cough monitoring endpoints for clinical trials and drug development. Objective, validated, and regulatory-ready.
Digital therapeutics for cough hypersensitivity. Apps that enable cough-centered digital care and cough as a treatable trait of respiratory conditions.
Empowering individuals to track, understand, and manage their cough.
Hyfe’s technology has collected millions of hours of cough data in over 50 studies worldwide. Our scientific partnerships span leading universities, global health organizations, and pharmaceutical companies.
Hyfe's patented AI architecture represents a fundamental breakthrough in passive health monitoring:
Optimized signal-processing + ML pipeline engineered to run on low-power silicon without degrading battery life or user experience.
Runs seamlessly from on-device (edge) to cloud, enabling continuous monitoring in any environment, on any hardware - from smartphones to wearables to clinical devices.
Robust performance across diverse microphones, environments, and device ecosystems, eliminating the usual calibration and retraining overhead.
Verified against gold-standard clinical recordings.
Automatic wear / non-wear detection, uptime reporting, and data-quality scoring ensure reliable endpoints and superior participant compliance.
Flexible integration into digital health ecosystems.
No audio recording. Hyfe detects coughs locally and records & transmits only metadata (timestamps). This ensures regulatory-grade privacy and dramatically reduces compliance burden. It also leads to better science.
Hyfe's patented AI architecture represents a fundamental breakthrough in passive health monitoring:
Neural networks run entirely on-device, analyzing only timestamps, never recording sounds
Models trained on the world’s largest cough dataset.
No internet connection required for basic detection; deployable globally
Works on any microphone-enabled device—smartphones, wearables, smart home devices
The latest from Hyfe’s research, partnerships, and scientific community.
Comprehensive Chronic Cough Report reveals $15B opportunity. 100M patients, zero FDA-approved drugs, positioning digital cough monitoring as essential pharma infrastructure.
Review including Hyfe research evaluates continuous digital cough monitoring as a practical way to address limitations of patient-reported cough data
Study results demonstrate digital Behavioral Cough Suppression Therapy reduced cough frequency by over 40% in patients with refractory and unexplained chronic cough.
Strategic partnership with KYORIN Pharmaceuticals aims to improve outcomes and expand treatment access to millions impacted by chronic cough globally.
With Hyfe, you can detect and track cough in real time, remotely and at scale
