Hyfe measures cough as an objective, continuous signal and trial endpoint so respiratory research can move beyond subjective reports and short cough recording windows.

Our validated, privacy-preserving, on-device detection quantifies cough frequency and patterns in real-world conditions with high participant adherence, producing data that is clinically interpretable and operationally practical at scale. Hyfe’s cough monitoring technology takes participant privacy extremely seriously and at no point conversations or audio can be listened to, there are no audio recordings stored, just timestamps of coughs processed in real time as the system passively monitors ambient sound levels.

This is increasingly essential as cough frequency has become an efficacy endpoint in FDA-reviewed chronic cough programs and regulatory expectations continue to sharpen around measurement validity, traceability, and interpretability.

Hyfe is built to deliver regulator-grade objective cough endpoints and trend insights (cough bouts, cough-free time, cough variability, among other) without adding burden for patients, sites, or study teams.