Cough Science Forum
Signal or Noise? Analyzing Measurement Bias in Cough Trials
New evidence for a Hawthorne effect in cough, and what it means for trial design and sample size.
Tuesday, October 6, 2026
8:00 AM PT · 11:00 AM ET · 5:00 PM CEST
Online · 60 minutes
Speakers

Joe Brew
Chief Data Scientist, Hyfe

Professor Giovanni Ferrara
University of Alberta
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About this session
Does monitoring change the cough?
Continuous cough monitoring promised objective, unbiased data in clinical trials. But what if the act of monitoring itself changes the cough it's measuring?
At this Cough Science Forum, we will present and analyze new evidence for a Hawthorne effect in cough, show real patient cases showing behavior shift under observation, and discuss what it means for trial design and sample size across therapeutic areas.
Professor Giovanni Ferrara (University of Alberta) joins with interim findings from an ongoing IPF study, extending the question to a disease where this effect hasn't yet been tested.
For researchers, trial designers, and anyone building an endpoint around patient-reported or device-measured cough, this session asks questions relevant for your next protocol.
Previous Forum
Temporal Dynamics of Cough Across Diseases
In our July 2026 session, three researchers presented continuous cough monitoring data across refractory chronic cough, COPD, and pediatric asthma — comparing, for the first time, how cough behaves over time across different diseases.
Prof. Fan Chung on 28-day monitoring in RCC, Dr. Carlos Chaccour on cough as a predictor of COPD exacerbations, and Dr. Mees Stoop on nocturnal cough in children with asthma. Moderated by Dr. Peter Small.
60 minutes. Free to watch.
Speakers

Refractory & Unexplained Chronic Cough
Professor Fan Chung, MD, DSc
Imperial College London

COPD
Dr Carlos J. Chaccour, MD
University of Navarra

Pediatric Asthma
Dr Mees Stoop, MD
Juliana Children's Hospital, The Hague
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