News & Updates
Interested in learning more about Hyfe? Read about all of our news, announcements and updates here!
Interested in learning more about Hyfe? Read about all of our news, announcements and updates here!
Comprehensive Chronic Cough Report reveals $15B opportunity. 100M patients, zero FDA-approved drugs, positioning digital cough monitoring as essential pharma infrastructure.
Review including Hyfe research evaluates continuous digital cough monitoring as a practical way to address limitations of patient-reported cough data
Study results demonstrate digital Behavioral Cough Suppression Therapy reduced cough frequency by over 40% in patients with refractory and unexplained chronic cough.
Strategic partnership with KYORIN Pharmaceuticals aims to improve outcomes and expand treatment access to millions impacted by chronic cough globally.
Hyfe’s AI-powered cough monitoring is now available on Actigraph’s FDA-cleared LEAP wearable, enabling continuous, privacy-preserving cough tracking alongside key health biomarkers
Clinical Trial Results Demonstrate Alkaline Magnesium-Based Salt Aerosol Reduced Cough Frequency by up to 35% in Refractory Chronic Cough Patients with Cough Counts Measured Continuously by AI-Powered tech
Hyfe's cough tracker was used in study by University of Navarra, revealing significant variability in cough patterns. This breakthrough highlights potential for continuous, objective chronic cough monitoring.
CoughPro app introduces the world’s first digital Cough Management feature, offering AI-driven solutions for millions suffering from chronic cough.
Research demonstrates the accuracy of Hyfe’s automated cough monitoring process and is the first to observe differences in type and length of cough between men and women.
AI company transitions app to subscription model and adds exclusive new features for users in the UK, Canada, Europe and global users outside the U.S.
Hyfe's technology integrated into ActiGraph’s new FDA-cleared LEAP wearable device that will advance the use of remote patient monitoring in chronic cough clinical research.
Studies show remote patient monitoring technology better predicts cough exacerbations to ultimately improve quality of life and reduce healthcare costs for patients with chronic cough.
Hyfe is expanding into chronic cough treatment with the world's first digital therapeutic for cough, using a proprietary model that combines real time cough frequency with cough suppression therapy.
150 winners selected out of 13,000 private companies; Hyfe recognized for contributions in screening, monitoring and diagnostics technologies
Hyfe has entered into an agreement with Merck, to integrate its artificial intelligence-powered (AI) cough tracker technology into Merck’s consumer disease educational efforts.
Leader in acoustic epidemiology empowers health care providers, researchers, pharmaceutical companies, and patients with cough detection and classification platform
Scientists use Hyfe to confirm that continuous cough monitoring for Long COVID was more sensitive in evaluating cough variability and response to treatment compared to patient reported outcomes.
Dr. Peter Small, Hyfe Chief Medical Officer has delivered deliver an intervention to the G20 Meeting in Yogyakarta, Indonesia, on the role of digital innovation in addressing public health crises.
With apps and artificial intelligence, researchers want to use the cough to better diagnose asthma, Covid-19 and other respiratory illnesses
Accomplished physician, scientist, and product developer to lead Hyfe's efforts as it seeks to transform patient care through cough monitoring and diagnosis.
Strategic partnership with KYORIN Pharmaceuticals aims to improve outcomes and expand treatment access to millions impacted by chronic cough globally.
Wilmington, Del., February 24, 2025 -- Hyfe, Inc., the global leader in AI-powered respiratory care, today announces its partnership with KYORIN Pharmaceutical Co. Ltd for the development and commercialization of the world’s first prescription digital therapeutic (DTx) to treat chronic cough in the Japanese market. Built on the proven principles of Behavioral Cough Suppression Therapy (BCST) and powered by Hyfe’s advanced cough monitoring technology, this collaboration marks a significant milestone in leveraging advanced digital therapeutics to address a debilitating condition that affects millions worldwide.
This is a major step forward in addressing a highly underserved medical condition; by transforming a therapy previously confined to in-person settings, we are dramatically expanding access to millions worldwide who struggle with chronic cough. By combining KYORIN’s extensive expertise in respiratory medicine and our powerful AI, the partnership is creating opportunities for deeper patient engagement, more precise treatment understanding, and improved patient outcomes. Together, we’re taking on chronic cough management and revolutionizing respiratory health care.
Dr. Peter Small
Chief Medical Officer at Hyfe
Chronic cough affects 10% of adults globally with a significant impact on their quality of life. The condition is often overlooked by traditional healthcare systems, particularly for underserved populations disproportionately affected, including women and older adults. Hyfe's innovative, non-invasive digital therapeutic addresses barriers to cough treatment by leveraging AI that unobtrusively monitors cough patterns with 90%+ accuracy on any mic-enabled device. This enables continuous, real-time tracking and personalized treatment interventions.
BCST, a non-pharmacological treatment method used to reduce chronic cough through cognitive-behavioral strategies, improves cough outcomes in up to 87% of patients. In addition, BCST has been shown to reduce cough in people with refractory chronic cough and unexplained chronic cough by 41%, significantly higher than any drug available on the market. However, BCST is only offered in-person by under 200 speech language pathologists in the U.S. and very few in Japan. Hyfe’s DTx bridges this gap by combining BCST with AI-powered cough monitoring to deliver personalized treatment plans on patients’ own mobile phones, empowering patients and providers to better treat the condition regardless of their geographic location.
The chronic cough market, valued at $17 billion and growing at 6.39% annually, represents a significant opportunity for digital therapeutics to transform care while reducing healthcare costs and improving patient outcomes.
To explore partnership opportunities or learn more about Hyfe’s digital therapeutic platform, visit hyfe.com or schedule a call here.
Hyfe, Inc. is the global leader in AI-powered cough-monitoring technology. The company’s patented machine-learning software enables passive, long-term monitoring of cough frequency, revealing novel health insights. Hyfe delivers cough-monitoring solutions that empower pharma and academic researchers to advance clinical trials, enable healthcare providers to optimize patient care, and power digital therapeutics to transform the management of respiratory illness, including chronic cough. Hyfe’s technology has been used in 50+ research studies, and its long-term partners include global pharma companies and leading academic institutions. More information is available at hyfe.com.
KYORIN Pharmaceutical Co., Ltd. was founded in 1923. Accelerating its evaluation and acquisition of in-licensed products and establishing a presence in designated fields, Kyorin aims to contribute broadly to people’s health by pursuing innovation in drug discovery, in order to strengthen drug discovery capability and create high-value new drugs that meet medical needs.
###
Media contact:
hyfe@ampublicrelations.com
_____________________________________
1 Arinze JT, de Roos EW, Karimi L, Verhamme KMC, Stricker BH, Brusselle GG. Prevalence and incidence of, and risk factors for chronic cough in the adult population: the Rotterdam Study. ERJ Open Res. 2020 Apr 19;6(2):00300-2019. doi: 10.1183/23120541.00300-2019. PMID: 32337212; PMCID: PMC7167208. https://pmc.ncbi.nlm.nih.gov/articles/PMC7167208/
2 Slovarp, L.J., Jetté, M.E., Gillespie, A.I. et al. Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy. Lung 199, 263–271 (2021). https://doi.org/10.1007/s00408-021-00442-w
3 Chamberlain Mitchell SA, Garrod R, Clark L, Douiri A, Parker SM, Ellis J, Fowler SJ, Ludlow S, Hull JH, Chung KF, Lee KK, Bellas H, Pandyan A, Birring SS. Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial. Thorax. 2017 Feb;72(2):129-136. doi: 10.1136/thoraxjnl-2016-208843. Epub 2016 Sep 28. PMID: 27682331. https://pubmed.ncbi.nlm.nih.gov/27682331/
Comprehensive Chronic Cough Report reveals $15B opportunity. 100M patients, zero FDA-approved drugs, positioning digital cough monitoring as essential pharma infrastructure.
Review including Hyfe research evaluates continuous digital cough monitoring as a practical way to address limitations of patient-reported cough data
Study results demonstrate digital Behavioral Cough Suppression Therapy reduced cough frequency by over 40% in patients with refractory and unexplained chronic cough.
Strategic partnership with KYORIN Pharmaceuticals aims to improve outcomes and expand treatment access to millions impacted by chronic cough globally.