53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions

At CHEST 2025, held in Chicago, Illinois, Laurie Slovarp, PhD, CCC-SLP, professor at the University of Montana and certified speech pathologist, presented a poster on the development of a digital therapeutic designed to improve access to behavioral cough suppression therapy for patients with refractory chronic cough.

A large-scale trial examining the effect of azithromycin on the relationship between oesophageal function and cough as evaluated by Hyfe's cough monitoring technology in respiratory disease is feasible and acceptable to patients.

This study used Hyfe's wearable cough monitor during a 7-day run in, 28-day treatment, and 14-day follow-up period in patients with chronic bronchitis.

Periods of intense coughing (termed bouts, epochs or bursts) are particularly problematic for some coughers and may not be reflected by simply counting the number of coughs per day. This study explored how varying the definition of bouts yield different impressions of cough severity.
01.10.2024

The Hyfe Cough Monitor Suite allows for continuous, non-intrusive acoustic cough monitoring that can last for months. This allows the interpretation of longitudinal signals providing important insights for clinicians, researchers, drug developers and regulators. There were however concerns that coughs from non-user bystanders may contaminate the acoustic environment and skew the estimated cough rates.
We analysed 223 hours (almost 10 days) of monitoring submitted by non-coughing volunteers across ten different everyday environments. Acoustic contamination by non-participant coughs ranged from 0 coughs per hour in a restaurant/bar outdoors to 1.04 coughs per hour in a dense, indoor space (symposium) and the same rate for periods of grocery shopping.
Scenario 1 - office worker with a family: spends 8 hours sleeping at home with their partner, 8 hours in the office, 1 hour grocery shopping, 1 hour on public transportation, 1 hour in a restaurant, and 5 hours at home with family. They pick up 2.6 coughs from others in 24 hours.
Scenario 2 - business traveler: spends 7 hours sleeping at home with their partner, 5 hours on public transportation, 1 hour in a restaurant indoors, 1 hour in a bar outdoors, 5 hours at a symposium, 2 hours at home with family, and 3 hours alone in a hotel. They pick up 4.61 coughs from others in 24 hours.
This pilot study establishes a methodology for quantifying this phenomenon and offers preliminary evidence that non-user coughs have minimal impact on the cough estimates provided by the Hyfe Cough Monitor Watch in real-world settings.