53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
Hyfe pilot study tests a digital therapeutic combining passive cough monitoring with behavioral suppression techniques delivered through the CoughPro app.
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Independent ERS 2025 NeuroCOUGH trial uses the Hyfe Cough Tracker to test feasibility of studying azithromycin's effect on cough and oesophageal motility.
Independent ERS 2025 trial uses the Hyfe Cough Tracker to show azithromycin reduces objective cough frequency by week one in chronic respiratory disease.
Commissioned for the Thirteenth London International Cough Symposium, this narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
The authors trace the field from the bulky tape recorders of the 1950s through today's fully passive, privacy-preserving platforms, and compare the leading commercial systems across form factor, validation, privacy architecture, and clinical adoption. They synthesize CCM findings across refractory chronic cough, COPD, bronchiectasis, heart failure, GERD, and tuberculosis, showing how continuous data has surfaced insights invisible to single-session assessment, from day-to-day variability that makes 24-hour snapshots unreliable, to cough-based early warning signals for COPD exacerbations.
The review closes with forward-looking directions including digital therapeutics, public health surveillance, regulatory pathways, and the emerging discipline of "coughomics."
