53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Authored by Hyfe's R&D team, this review synthesizes work presented at the European Respiratory Society Congress 2025 and argues that objective cough monitoring has crossed a practical threshold, moving from experimental technique to deployable clinical endpoint.
At CHEST 2025, held in Chicago, Illinois, Laurie Slovarp, PhD, CCC-SLP, professor at the University of Montana and certified speech pathologist, presented a poster on the development of a digital therapeutic designed to improve access to behavioral cough suppression therapy for patients with refractory chronic cough.
This study asked whether the core components of BCST could be embedded in a digital therapeutic and paired with continuous, objective cough monitoring inside the CoughPro app.
Commissioned for the Thirteenth London International Cough Symposium, this narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
The authors trace the field from the bulky tape recorders of the 1950s through today's fully passive, privacy-preserving platforms, and compare the leading commercial systems across form factor, validation, privacy architecture, and clinical adoption. They synthesize CCM findings across refractory chronic cough, COPD, bronchiectasis, heart failure, GERD, and tuberculosis, showing how continuous data has surfaced insights invisible to single-session assessment, from day-to-day variability that makes 24-hour snapshots unreliable, to cough-based early warning signals for COPD exacerbations.
The review closes with forward-looking directions including digital therapeutics, public health surveillance, regulatory pathways, and the emerging discipline of "coughomics."
