53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
Hyfe pilot study tests a digital therapeutic combining passive cough monitoring with behavioral suppression techniques delivered through the CoughPro app.
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Independent ERS 2025 NeuroCOUGH trial uses the Hyfe Cough Tracker to test feasibility of studying azithromycin's effect on cough and oesophageal motility.
Independent ERS 2025 trial uses the Hyfe Cough Tracker to show azithromycin reduces objective cough frequency by week one in chronic respiratory disease.
01.10.2024
Real-time continuous cough monitoring using wearable technology is a novel technique of quantifying disease severity in patients with chronic cough. Little is known about how daily objective cough count measured by such devices correlates with subjective assessment of symptoms in cough patients.
Patients with chronic cough were monitored the Hyfe CoughMonitor for 30 consecutive days and concomitantly recorded daily cough severity scores using the Cough Visual Analogue Scale (VAS). Objective cough count data collected was recorded and correlated with daily VAS scores.
12 Patients recorded a median of 93 coughs per day (range 3-637) with a mean (SD) cough VAS score of 43mm (24mm). There was no significant association between daily cough count and daily cough VAS score in any of the patients. Scatter plots demonstrating these relationships can be visualised in Figure 1 and the Pearson correlation coefficients can be seen in Table 1.
There is no association between daily objective cough counts and daily cough VAS scores, more work is required to find the optimal endpoint for responses to treatment for chronic cough.
