53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
Hyfe pilot study tests a digital therapeutic combining passive cough monitoring with behavioral suppression techniques delivered through the CoughPro app.
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Independent ERS 2025 NeuroCOUGH trial uses the Hyfe Cough Tracker to test feasibility of studying azithromycin's effect on cough and oesophageal motility.
Independent ERS 2025 trial uses the Hyfe Cough Tracker to show azithromycin reduces objective cough frequency by week one in chronic respiratory disease.
04.09.2025
This randomized controlled trial tested whether behavioral cough suppression therapy, a treatment that normally requires in-person visits with a specialized speech-language pathologist, could be delivered entirely online.
Thirty adults with refractory chronic cough completed a 5-week program of asynchronous video and text modules, randomized against a healthy-lifestyle education control. At one week post-treatment, 72% of IBCST participants showed clinically significant improvement on the Leicester Cough Questionnaire, rising to 76% at one-month follow-up.
Qualitative interviews highlighted the convenience and perceived quality of the program. The findings support IBCST as a feasible, efficacious, and scalable foundation for a digital therapeutic.
