53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Authored by Hyfe's R&D team, this review synthesizes work presented at the European Respiratory Society Congress 2025 and argues that objective cough monitoring has crossed a practical threshold, moving from experimental technique to deployable clinical endpoint.
At CHEST 2025, held in Chicago, Illinois, Laurie Slovarp, PhD, CCC-SLP, professor at the University of Montana and certified speech pathologist, presented a poster on the development of a digital therapeutic designed to improve access to behavioral cough suppression therapy for patients with refractory chronic cough.
This study asked whether the core components of BCST could be embedded in a digital therapeutic and paired with continuous, objective cough monitoring inside the CoughPro app.
04.09.2025
This randomized controlled trial tested whether behavioral cough suppression therapy, a treatment that normally requires in-person visits with a specialized speech-language pathologist, could be delivered entirely online.
Thirty adults with refractory chronic cough completed a 5-week program of asynchronous video and text modules, randomized against a healthy-lifestyle education control. At one week post-treatment, 72% of IBCST participants showed clinically significant improvement on the Leicester Cough Questionnaire, rising to 76% at one-month follow-up.
Qualitative interviews highlighted the convenience and perceived quality of the program. The findings support IBCST as a feasible, efficacious, and scalable foundation for a digital therapeutic.
