53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
Hyfe pilot study tests a digital therapeutic combining passive cough monitoring with behavioral suppression techniques delivered through the CoughPro app.
This narrative review by Hyfe's R&D team makes the case that continuous cough monitoring (CCM), powered by acoustic AI, transforms cough from a subjective symptom into a quantifiable digital biomarker.
Independent ERS 2025 NeuroCOUGH trial uses the Hyfe Cough Tracker to test feasibility of studying azithromycin's effect on cough and oesophageal motility.
4 September 2025
This randomized controlled trial tested whether behavioral cough suppression therapy, a treatment that normally requires in-person visits with a specialized speech-language pathologist, could be delivered entirely online.
Thirty adults with refractory chronic cough completed a 5-week program of asynchronous video and text modules, randomized against a healthy-lifestyle education control. At one week post-treatment, 72% of IBCST participants showed clinically significant improvement on the Leicester Cough Questionnaire, rising to 76% at one-month follow-up.
Qualitative interviews highlighted the convenience and perceived quality of the program. The findings support IBCST as a feasible, efficacious, and scalable foundation for a digital therapeutic.
